Biological Activity for Cyclosporin H
Cyclosporin H is a viral transduction enhancer. Increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Displays an additive effect when combined with rapamycin (Cat. No. 1292) or prostaglandin E2 (Cat. No. 2296). Lacks immunosuppressant activity of cyclosporin A (Cat. No. 1101).
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Technical Data for Cyclosporin H
| M. Wt | 1202.64 |
| Formula | C62H111N11O12 |
| Storage | Store at -20°C |
| Purity | ≥97% (HPLC) |
| CAS Number | 83602-39-5 |
| PubChem ID | 6476564 |
| InChI Key | PMATZTZNYRCHOR-JLPRAAIDSA-N |
| Smiles | |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility Data for Cyclosporin H
| DMSO | 120.26 | 100 |
| ethanol | 60.13 | 50 |
Preparing Stock Solutions for Cyclosporin H
The following data is based on the product molecular weight 1202.64. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
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